Neena Thurman was one of the many children born to the U.S. government's Project: Armageddon, designed to genetically engineer the perfect weapon using a precognitive mutant named Beatrice. Domino was once captured by the arms dealer Tolliver, secretly Cable's estranged son Tyler, who had one of his agents impersonate Domino in Caple's new strike-team X-Force. Cable ultimately freed her and she came to aid him in his role as X-Force's leader.